Basic Science
Developmental Biology

Engineered Solutions for Health

Fertility and Hormone Preservation and Restoration

Host-Microbial Interactions, Inflammation, and Immunity

Human Molecular Genetics and Physiology

Immune Deviation and Disease

Injury, Repair, and Regeneration

Molecular and Translational Cancer Biology

Neurobiology

Perinatal Origins of Disease
Basic and Preclinical Science
We investigate essential functions of biological processes and fundamental mechanisms of diseases and disorders affecting children’s health. Our lab-based programs are organized into virtual scientific neighborhoods that promote collaborations.
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Clinical Trials

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Clinical and Community Trials
Our work translates the discoveries of basic science into promising clinical applications. Multidisciplinary teams of researchers collaborate on clinical research on a range of specialties and conditions organized into program areas.
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Population Science
Smith Child Health Outcomes, Research and Evaluation Center

Macy Laboratory

ARISE Health Laboratory

Center for Food Allergy and Asthma Research

Foster Health Laboratory

Genetics and Justice Laboratory

I+HEAL Laboratory

Pediatric Practice Research Group

TRICAM
Community, Population Health, and Outcomes
We drive the research on biological, psychological, social, behavioral, and environmental causes and influencers of common and prominent child health problems to generate evidence for clinical and public health interventions.
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Quantitative Science
Clinical Research Informatics

Data, Discovery, and Development

Data Science and Analytics

Research Information Technology
Quantitative Science
The Quantitative Science pillar provides cutting-edge statistical and analytical support and computational techniques to maximize research impact and improve the health outcomes of pediatric patients.
Researchers
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Loretta S Li
Our Researchers
Our diverse team of researchers are influential leaders in investigating pediatric health issues and diseases, and include physicians, scientists, postdocs, coordinators, statisticians, data analysts, trainees, and others who routinely collaborate with medical centers, academic institutions, and community partners across the globe.
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Loretta S. Li, MD

Basic and Preclinical Science
Li (Loretta) Laboratory

Biography

Attending Physician, Hematology, Oncology, Neuro-Oncology & Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago
Assistant Professor of Pediatrics (Hematology, Oncology, and Stem Cell Transplantation), Northwestern University Feinberg School of Medicine

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Education and Background

Fellowship in Pediatric Hematology Oncology, Boston Children's Hospital 2012-2015
Residency in Pediatrics, Boston Children's Hospital 2009-2012
Harvard Medical School 2009

Publications

Sep. 27, 2023

PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation.

Jun. 07, 2023

New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation.

Mar. 25, 2023

Multifocal bone marrow disease in a young female with myeloid sarcoma.

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Stanley Manne Children's Research Institute
Louis A. Simpson and Kimberly K. Querrey Biomedical Research Center

303 East Superior Street
Chicago, IL 60611

	
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